Science education research

Course-based undergraduate research experiences (CUREs) put real research questions into regular courses, so every enrolled student does research rather than a few in a faculty lab. This research area studies how those courses are taught, assessed and sustained, much of it with the faculty community of SEA-PHAGES, the HHMI program in which students find and sequence new bacteriophages. It also covers the research students produce: the phage genome announcements they co-author. The Tarleton phage hunting course itself, with what students do each semester and the full discovery guide, is on the Phage Discovery Program page.

Course-based research as a subject of study#

SEA-PHAGES is a large, long-running CURE: students at many member schools isolate phages, and every phage goes into the shared database, PhagesDB. More about the national program is at seaphages.org. Because so many faculty teach the same research at different institutions, the program is a natural place to ask how research courses work: how instructors teach them, how they grade research whose answer is not known in advance, what it means to be both a scientist and a teacher, and how a community of faculty keeps improving a shared course. The papers below come out of that work.

Classroom materials#

Genome announcements students co-author#

A CURE ends in results that others can use. In the Tarleton program, once a phage genome is sequenced and annotated, the class writes it up as a short genome announcement in Microbiology Resource Announcements, with the students as co-authors. The published announcements from this program and its partners:

Phage Host Notes Paper
Godfather Microbacterium foliorum Erath County soil; 17,452 bp, 24 genes, cluster EE 2025
Loca Microbacterium foliorum From a shopping-cart handle swab, Erath County; 17,475 bp, 25 genes 2022
Fizzles Microbacterium foliorum Anthill soil, Erath County; 62,078 bp, 104 genes 2022
IndyLu Microbacterium foliorum Erath County soil; 41,958 bp, 71 genes, one tRNA 2021
Joy99 Mycobacterium smegmatis Annotated by high school students at a partner school; 59,837 bp, 97 genes 2021
Tripl3t and Zeuska Mycobacterium smegmatis Annotated by high school students at partner schools; about 53,600 bp each 2021
Finny Microbacterium foliorum 40,313 bp, 63 genes 2019
Ryadel Mycobacterium smegmatis Cluster O, elongated head; 72,658 bp, 132 genes 2019
Arlo Mycobacterium smegmatis Erath County soil; 52,960 bp, 96 genes, cluster A1 2018

Every phage the program has found, published or not, is in the phage table. The full list of papers is under publications.

Phages may become a next generation of treatment for antibiotic-resistant bacterial infections. A survey of US healthcare providers' views of phage therapy (International Journal of Environmental Research and Public Health, 2025) found that 49 percent of 196 clinicians knew about it and 56 percent would consider using it.